Cyclobenzaprine an overview

Speak to your doctor about how any drug interactions are being managed or should be managed. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor zanaflex compared to flexeril has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. Call your doctor or local poison control center immediately if you have an allergic reaction.

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Therefore, this drug should only be used in pregnancy if clearly needed. Many insurance companies require prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. You should not need a new prescription for this medication to be refilled.

Our writers and reviewers are experienced professionals in medicine, addiction treatment, and healthcare. AddictionResource fact-checks all the information before publishing and uses only credible and trusted sources when citing any medical data. The Verified badge on our articles is a trusted sign of the most comprehensive scientifically-based medical content. If you have any concern that our content is inaccurate or it should be updated, please let our team know at [emailprotected]. Other drugs with moderate interactions like that of alcohol, weed, and Ibuprofen include Benadryl (Diphenhydramine), Gabapentin (Neurontin), Ambien (Zolpidem), and Xanax (Alprazolam). These drugs may heighten the risk of side effects such as drowsiness, disorientation or lightheadedness, and mental impairment.

Warnings for people with certain health conditions

Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Acute recovery phase of myocardial infarction, and patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure. Pharmacologic similarities among the tricyclic drugs require that certain withdrawal symptoms be considered when FLEXERIL is administered, even though they have not been reported to occur with this drug. Abrupt cessation of treatment after prolonged administration rarely may produce nausea, headache, and malaise. When it comes to the matter of drug interactions between Cyclobenzaprine and other drugs, there is a lot to look out for and factors to be considered.

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If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Using drinks containing alcohol can increase your risk of dizziness, drowsiness, and decreased alertness from cyclobenzaprine. Elderly patients seem to tolerate cyclobenzaprine less and may develop hallucinations as well as significant anticholinergic side effects, such as sedation. The use of significant lower dosing schedules in elderly patients may be prudent. The most common adverse reactions to cyclobenzaprine are somnolence, dry mucous membranes, dizziness, and confusion.

Drugs Affecting Nicotinic Receptors∗

The combination of Cyclobenzaprine and alcohol, for instance, may result in tolerance, dependency, and abuse — this is also true for other drug combinations. Furthermore, it is important to consider how long Flexeril lasts. Nevertheless, recovery is possible for people struggling with substance addiction. The first step to take would be contacting the drug abuse rehab representatives for assistance. There are many addiction recovery programs available to get rid of the menace of dependence.

• Use of this medication is not recommended for periods longer than 2 or 3 weeks.
• The overall effectiveness of FLEXERIL was similar to that observed in the double-blind controlled studies; the overall incidence of adverse effects was less (see ADVERSE REACTIONS).
• Remaining abstinent from substances that the body has become physiologically dependent upon can be difficult without support.

Selection of a skeletal muscle relaxant should be individualized to the patient. If there are tender spots over the muscle or trigger points on physical examination, a skeletal muscle relaxant is a reasonable adjunct to analgesic treatment of low back pain. Skeletal muscle relaxants may also be used as an alternative to NSAIDs in patients who are at risk of gastrointestinal or renal complications. This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness).

Minor Interactions

Do not start, stop, or change the dosage of any medicines without your doctor’s approval. It is structurally similar to the tricyclic antidepressants and adverse effects similar to those seen with the tricyclic antidepressants are therefore to be expected. Patients with low back pain or fibromyalgia may benefit from treatment with cyclobenzaprine. Recent evidence showed similar effectiveness at half of its manufacturer recommended dose (5 mg), but with fewer adverse effects.33 It may optimally be used in younger patients with limited or no medical conditions. Higher doses of cyclobenzaprine or tizanidine would be appropriate to promote sedation in cases of more severe discomfort or perceived muscular spasm. Although there appears to be insufficient data on metaxalone and methocarbamol, these may be useful in patients who cannot tolerate the sedative properties of cyclobenzaprine or tizanidine.

Call 911 or go to the nearest emergency room if your symptoms are severe. Do not take this drug again if you’ve ever had an allergic reaction to it. If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist. It is also possible for serious cyclobenzaprine side effects to occur, like seizures, heart arrhythmias, heart attack, or stroke.

This is more likely to happen in the few hours after you take it. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. However, the half-life of immediate-release cyclobenzaprine is 18 hours on average, with a range of 8-37 hours. The extended-release form typically has a half-life of hours. Drowsiness, dizziness, dry mouth, abdominal pain, acid regurgitation, constipation, diarrhea, nausea, irritability, mental acuity decreased, nervousness.